Advanced Light Microscopy, Immunobiology
Yale School of Engineering and Applied Science
We are currently focusing on identifying the in vivo source of TAM ligands, unraveling the molecular determinants that account for the specificity of TAM-mediated inhibition, and testing the role of TAM-mediated immune suppression in vivo. Our long-term goal is to manipulate this pathway as an innovative therapeutic strategy for the inhibition or enhancement of the inflammatory response.