PROMOTING SCIENCE AND TECHNOLOGY BETWEEN INDIA AND THE U.S.
Biochemistry, Molecular Biology
Michigan State University
Our research focuses on a fundamental biological question, how membrane proteins are made and destroyed in cells. Membrane proteins comprise approximately 30% of all proteins encoded in genes and carry out numerous critical functions. The folding problem of membrane proteins is directly related to human health. Indeed, accumulation of misfolded membrane proteins causes serious diseases such as Alzheimer’s disease, cystic fibrosis, and cancer. To answer our cardinal question, we investigate two conceptually connected biological processes by biochemical and biophysical methods.