Chemical Engineering
University of Southern California
Research interests:
Tissue engineering involves the triad of biomaterial science, growth factor delivery, and molecular biology to engineer devices for cell immobilization and tissue regeneration. Jabbari’s research draws upon chemistry, biology, macromolecular science and exploits biomimetic strategies to engineer cellular constructs for regeneration of skeletal tissues. Biologically-inspired materials combined with micro/nanoscale technologies can potentially create constructs to support delivery, differentiation, and maturation of progenitor cells to multiple lineages to regenerate complex tissues like bone and cartilage. Current projects include (1) bio-inspired multiscale constructs for regeneration of load-bearing large bone segments, (2) micro-patterned cellular constructs with gradient of growth factors for concurrent induction of osteogenesis and vasculogenesis, (3) multilayer gradient constructs for the regeneration of articular cartilage, (4) cancer stem cell mechanotransduction in an engineered matrix, and (4) synthesis of self-assembled nanogels for the delivery of multiple growth factors in regenerative medicine.