Host: Cold Spring Harbor
Maharrish was working on tumor microenvironment. Immune cells, Endothelial cells, Stromal cells and Extra cellular matrix constitutes microenvironment which are all vital drivers for metastasis. He was working on CCR2 (molecule expressed by myeloid and tumor cells which is important for metastasis) Knock out mice and characterizing the efficacy of adopted CD8+ T cell transfer. He is also characterizing the antigens released by irradiated tumor cells that can activate Dendritic cells for active presentation and ultimately these antigens can be used in tumor therapeutic next generation vaccine.
