Biology, Cell Biology, Molecular Biology
Massachusetts Institute of Technology
The Martin lab is interested in how tissues get into shape. Understanding tissue shape requires understanding how cells generate force and how cells work together to collectively sculpt a tissue. We have elucidated how cells generate force and how this force is propagated to the tissue-level to fold a tissue. In addition, we are interested in how tissue integrity is regulated and also investigate mechanisms that regulate the epithelial-to-mesenchymal transition or EMT. Finally, work in the lab also addresses the interplay between tissue forces and cell division.