Cell Biology, Materials Science, Pharmaceutical Sciences
University of Pittsburgh
The goal of our laboratory is to develop an independent and multidisciplinary research program at the interface of biomaterials, controlled drug delivery, and tissue engineering. We use interdisciplinary approach to build biomimetic microenvironments in vitro based on our expertise in the Pharmaceutical Sciences, Materials Sciences, Cell Biology and Micro/nanotechnologies. Specifically, we aim to develop tissue-engineered tumor models that recreate the three-dimensional structure, cell-cell/cell-matrix interaction, stromal environments, and signalling cues present in vivo. These three-dimensional models will be used for understanding the pathophysiology of the disease as well as for preclinical evaluation of drug safety and efficacy.