Kallol Gupta is an assistant professor at the Yale School of Medicine, Department of Cell Biology, Nanobiology Institute. His lab’s interest is to discover the novel transient membrane and membrane associated multiprotein complexes formed during the progression of different cellular signalling pathways. With more than 60% marketed drugs targeting membrane proteins, a detail understanding
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Research Area: Weed biology and management for ornamental crop productions, Horticultural science. Michigan is one of the largest producers of ornamentals and third largest producer of Christmas tree production in the United States. There are about 705 greenhouse operations producing $472 million worth of ornamental crops. Weeds are a major issue in these ornamentals and
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Our Focus Our group’s research interests are firmly rooted in employing the power of organic synthesis for medicinal chemistry and materials chemistry applications. To this end, we develop novel reagents and methodologies with a thorough understanding of their mechanistic aspects to facilitate the synthesis of a variety of simple and complex molecular targets. As a member of three of Purdue’s Discovery Park Centers: (i) Purdue Institute for Drug Discovery (ii) Purdue
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Research in the Rienstra group aims to establish solid state nuclear magnetic resonance (SSNMR) as a preferred method for routine, atomic resolution structural and dynamic analysis of biological macromolecules. The field of SSNMR is in the midst of a revolution not unlike the advances in X-ray crystallography that occurred during the 1970’s, and solution NMR
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Our research program covers a wide range of materials science disciplines, with a general focus on the formation and study of nano and microstructures through self and directed assembly. Materials containing structure on these length scales have been found to exhibit interesting and important electrical, optical, mechanical and biological properties. We often use and develop
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The Device Research and Engineering Laboratory at the University of Pennsylvania, led by Prof. Deep Jariwala is engaged in the study, design and development of nanometer and atomic scale devices, materials and interfaces for applications in computing, sensing, information technology and renewable energy. Our research is highly inter-disciplinary involving expertise from Electrical Engineering, Materials Science,
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My laboratory fosters a multidisciplinary environment that bridges physics, chemistry and biology with the aim of training undergraduate, graduate and medical students towards aligning their interests in challenging questions in cancer. We constantly interact with biomedical engineers, medical and radiation oncologists and pathology experts to further our understanding of the clinical manifestations of the various
Read MoreEarly stages in modern drug discovery often involve screening small molecules for their effects on a selected protein target or a model of a biological pathway. In the past fifteen years, innovative technologies that enable rapid synthesis and high throughput screening of large libraries of compounds have been adopted in almost all major pharmaceutical and
Read MoreFor decades, quantum chemists have been forced to make an oftentimes humbling choice in their day-to-day work: to use highly accurate, many-body methods that are too slow to apply to realistic quantum systems, or, to use faster one-body methods that are significantly less accurate. This fundamental compromise has glaringly limited the impact of quantum chemistry.
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Dr. Tiwari has a keen interest at the interphase of chemistry and biology with a focus on using peptides and small molecules in solving biological problems. Major areas of interest include developing CN2097 peptide analogs for neurotherapeutics, synthesizing fatty acyl derivatives of antibacterial peptides for MRSA, developing peptide-drug conjugates (PDC) for prostate cancer targeted therapy.
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